Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545940 | 1.00 | TDO2 (0.37) | TDO2SGK1GPR84CCR2NR3C1 | |
| SCHEMBL20344344 | 0.91 | SLC40A1 (0.39) | TDO2SGK1PPARGSLC40A1CCR4 | |
| SCHEMBL20354864 | 0.87 | TDO2 (0.39) | TDO2SGK1GPR84CCR2SLC40A1 | |
| SCHEMBL20339198 | 0.85 | SGK1 (0.39) | TDO2SGK1CCR2SLC40A1NR4A2 | |
| SCHEMBL20344324 | 0.82 | CCR4 (0.44) | SGK1CCR2SLC40A1CCR4NR4A2 | |
| SCHEMBL20355340 | 0.82 | SGK1 (0.40) | TDO2SGK1GPR84CCR2SLC40A1 | |
| SCHEMBL21545889 | 0.81 | TDO2 (0.39) | TDO2SGK1GPR84CCR2NR3C1 | |
| SCHEMBL30286554 | 0.81 | TDO2 (0.39) | TDO2SGK1GPR84CCR2NR3C1 | |
| SCHEMBL20354925 | 0.81 | SGK1 (0.36) | TDO2SGK1CCR2ALPLNR4A2 | |
| SCHEMBL20354911 | 0.81 | CCR4 (0.39) | TDO2SGK1CCR2CCR4ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |