Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 3/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288286 | 0.85 | RXFP1 (0.44) | RXFP1CRHR1CNR2IDH1PIM1 | |
| SCHEMBL30288260 | 0.84 | RXFP1 (0.54) | RXFP1CRHR1IDH1PIM1LIPC | |
| SCHEMBL1241128 | 0.79 | RXFP1 (0.61) | RXFP1CRHR1PIM1LIPCLIPG | |
| SCHEMBL30288262 | 0.79 | RXFP1 (0.61) | RXFP1CRHR1PIM1LIPCLIPG | |
| SCHEMBL13439179 | 0.78 | RXFP1 (0.49) | RXFP1CRHR1PIM1LIPCLIPG | |
| SCHEMBL11935445 | 0.78 | RXFP1 (0.49) | RXFP1CRHR1PIM1LIPCLIPG | |
| SCHEMBL13438988 | 0.75 | CRHR1 (0.48) | RXFP1CRHR1CNR2LIPCLIPG | |
| SCHEMBL30288245 | 0.73 | CNR2 (0.39) | RXFP1CRHR1CNR2IDH1LIPC | |
| SCHEMBL30288292 | 0.73 | IDH1 (0.43) | RXFP1CRHR1CNR2IDH1LIPC | |
| SCHEMBL4369018 | 0.73 | CRHR1 (0.52) | CRHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, MPST, CRAT | RXFP1 931/4885CRHR1 4608/4885CNR2 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.