Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.47 |
| ▸ | LIPC | P11150 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 3/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241128 | 1.00 | RXFP1 (0.61) | RXFP1LMNAALDH1A1EPHX2GAA | |
| SCHEMBL30288260 | 0.94 | RXFP1 (0.54) | RXFP1LMNAALDH1A1EPHX2GAA | |
| SCHEMBL13439179 | 0.87 | RXFP1 (0.49) | RXFP1LMNAALDH1A1CRHR1LIPC | |
| SCHEMBL11935445 | 0.87 | RXFP1 (0.49) | RXFP1LMNAALDH1A1CRHR1LIPC | |
| SCHEMBL30288286 | 0.81 | RXFP1 (0.44) | RXFP1LMNAALDH1A1EPHX2GAA | |
| SCHEMBL1241605 | 0.80 | LIPC (0.46) | RXFP1LMNAALDH1A1EPHX2CRHR1 | |
| SCHEMBL30288233 | 0.79 | RXFP1 (0.42) | RXFP1ALDH1A1CRHR1LIPCLIPG | |
| SCHEMBL1241972 | 0.78 | PIM1 (0.48) | ALDH1A1EPHX2GAAPOLBPIM1 | |
| SCHEMBL13438988 | 0.77 | CRHR1 (0.48) | RXFP1CRHR1LIPCLIPG | |
| SCHEMBL12204104 | 0.77 | MEN1 (0.44) | RXFP1LMNAALDH1A1EPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, MPST, CRAT | RXFP1 931/4885LMNA 2631/4885ALDH1A1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.