Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288260 | 0.75 | RXFP1 (0.54) | CRHR1IDH1IDH2RXFP1LIPC | |
| SCHEMBL28168097 | 0.75 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL29072670 | 0.74 | PDK2 (0.43) | IDH2SIGMAR1BACE1ICMT | |
| SCHEMBL30288233 | 0.73 | RXFP1 (0.42) | CNR2CRHR1IDH1TLR7IDH2 | |
| SCHEMBL30288286 | 0.73 | RXFP1 (0.44) | CNR2CRHR1IDH1TLR7IDH2 | |
| SCHEMBL30288292 | 0.73 | IDH1 (0.43) | CNR2CRHR1IDH1TLR7IDH2 | |
| SCHEMBL4369018 | 0.73 | CRHR1 (0.52) | CRHR1ICMT | |
| SCHEMBL16275260 | 0.72 | KDM4E (0.38) | CRHR1BACE1BACE2ICMTCARM1 | |
| SCHEMBL1241128 | 0.70 | RXFP1 (0.61) | CRHR1RXFP1LIPCLIPGPOLB | |
| SCHEMBL30288262 | 0.70 | RXFP1 (0.61) | CRHR1RXFP1LIPCLIPGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, MPST, CRAT | CNR2 2375/4885CRHR1 4608/4885IDH1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.