Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908507 | 0.86 | ENPP2 (0.47) | TAAR1NOS1KIF11MAOBHTR2C | |
| SCHEMBL24351980 | 0.84 | TAAR1 (0.61) | TAAR1DRD2DRD1NOS1KIF11 | |
| SCHEMBL2911870 | 0.82 | TAAR1 (0.67) | TAAR1DRD2DRD1NOS1KIF11 | |
| SCHEMBL1908555 | 0.82 | KIF11 (0.44) | TAAR1KIF11HTR2CCYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL14157546 | 0.80 | TAAR1 (0.65) | TAAR1DRD2DRD1NOS1KIF11 | |
| SCHEMBL4449174 | 0.80 | TAAR1 (0.70) | TAAR1DRD2DRD1NOS1KIF11 | |
| SCHEMBL15045357 | 0.79 | CNR1 (0.47) | TAAR1MAPK1ACHESMN1; SMN2CYP1A2 | |
| SCHEMBL21177003 | 0.79 | CYP1A2 (0.37) | TAAR1CYP1A2CYP2C19 | |
| SCHEMBL15504962 | 0.79 | MEN1 (0.40) | TAAR1KIF11TSHRHTR2CACHE | |
| SCHEMBL18434546 | 0.79 | TAAR1 (0.73) | TAAR1DRD2DRD1NOS1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, MPST, CRAT | TAAR1 3524/4885DRD2 4742/4885DRD1 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.