SCHEMBL30289323

SCHEMBL30289323

O=C1CN=C(c2ccc[nH]2)c2cc(Cl)ccc2N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 1.00
▸ MEN1 O00255 1/20 1.00
▸ PDE4D Q08499 2/20 0.68
▸ CNR1 P21554 1/20 0.68
▸ NTSR1 P30989 1/20 0.68
▸ OPRK1 P41145 1/20 0.68
▸ GABRA1 P14867 7/20 0.67
▸ GABRA5 P31644 7/20 0.67
▸ GABRA3 P34903 7/20 0.67
▸ GABRA2 P47869 7/20 0.67
▸ GABRB2 P47870 6/20 0.67
▸ GABRG2 P18507 5/20 0.67
▸ GABRB3 P28472 5/20 0.67
▸ GABRP O00591 3/20 0.67
▸ GABRD O14764 3/20 0.67
▸ GABRB1 P18505 3/20 0.67
▸ GABRA4 P48169 3/20 0.67
▸ GABRE P78334 3/20 0.67
▸ GABRA6 Q16445 3/20 0.67
▸ GABRG1 Q8N1C3 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8844868 1.00 KMT2A (1.00) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL9686097 0.86 MEN1 (0.75) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL30297595 0.84 KMT2A (0.73) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL9563515 0.84 KMT2A (0.73) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL9563509 0.84 KMT2A (0.73) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL23424295 0.84 KMT2A (0.73) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL9422490 0.84 KMT2A (0.73) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL15400204 0.84 KMT2A (0.72) KMT2AMEN1PDE4DCNR1NTSR1
SCHEMBL9684191 0.83 KMT2A (0.71) KMT2AMEN1PDE4DCNR1NTSR1
Ro-24-7429 SCHEMBL29736766 0.83 MEN1 (0.70) KMT2AMEN1PDE4DCNR1NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144066-A1 Prevention and Treatment of Parasitic Infections BARANOWITZ STEVEN (US) 2025-05-08 — — US disclosed
WO-2025064458-A1 PREVENTION AND TREATMENT OF VIRAL INFECTIONS BARANOWITZ STEVEN (US) 2025-03-27 — — WO disclosed
US-20230313325-A1 METHODS FOR DETECTION OF PATHOGENIC INFECTIONS USING RED BLOOD CELL-CONTAINING PATIENT SAMPLES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-10-05 — — US disclosed
EP-4146820-A1 METHODS FOR DETECTION OF PATHOGENIC INFECTIONS USING RED BLOOD CELL-CONTAINING PATIENT SAMPLES The Trustees of The University of Pennsylvania (US) 2023-03-15 — — EP disclosed
EP-4138853-A1 METHODS AND MATERIALS FOR TREATMENT OF FIBROSIS The Schepens Eye Research Institute, Inc. (US) 2023-03-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250144066-A1 Prevention and Treatment of Parasitic Infections EPX, CTSA, SERPINB1 KMT2A 2561/4885MEN1 2783/4885PDE4D 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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