Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844868 | 0.86 | KMT2A (1.00) | MEN1KMT2ACHRM1ALDH1A1PKM | |
| SCHEMBL30289323 | 0.86 | KMT2A (1.00) | MEN1KMT2ACHRM1ALDH1A1PKM | |
| SCHEMBL11833513 | 0.85 | MEN1 (0.54) | MEN1KMT2ACHRM1ALDH1A1PKM | |
| Ro-24-7429 SCHEMBL29736766 | 0.81 | MEN1 (0.70) | MEN1KMT2ACHRM1ALDH1A1PKM | |
| SCHEMBL29627864 | 0.80 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7323716 | 0.80 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7330628 | 0.79 | ALOX12 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL11824724 | 0.79 | CHRM1 (0.70) | MEN1KMT2ACHRM1ALDH1A1PKM | |
| SCHEMBL7322840 | 0.77 | CHRM1 (0.77) | MEN1KMT2ACHRM1ALDH1A1PKM | |
| SCHEMBL7328311 | 0.77 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141735-A | Viricides for AIDS treatment | HOFFMAN-LA ROCHE, INC. (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0475231-A1 | Benzodiazepines | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| EP-0462522-A1 | Aminobenzodiazepines | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-27 | — | — | EP | disclosed |