Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289853 | 0.86 | MAPT (0.48) | POLA1LCKMAPTMEN1KMT2A | |
| SCHEMBL30289906 | 0.83 | POLA1 (0.57) | POLA1LCKMAPTMEN1KMT2A | |
| SCHEMBL30289841 | 0.82 | MAPT (0.40) | POLA1TAAR1LCKMAPTMEN1 | |
| SCHEMBL30289893 | 0.81 | AKT1 (0.40) | LCKKDM4EEGFRSMN1; SMN2ALDH1A1 | |
| SCHEMBL30289811 | 0.77 | MAPT (0.40) | POLA1TAAR1LCKMAPTMEN1 | |
| SCHEMBL30289798 | 0.76 | MAPT (0.45) | TAAR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30289899 | 0.76 | CXCR2 (0.41) | POLA1LCKEGFRSRCZAP70 | |
| SCHEMBL30289806 | 0.74 | MAPT (0.45) | POLA1TAAR1MAPTMEN1KMT2A | |
| SCHEMBL30289871 | 0.71 | KDM4E (0.49) | LCKKDM4EEGFRSRCZAP70 | |
| SCHEMBL30289914 | 0.70 | PARP1 (0.56) | TAAR1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |