Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.45 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.45 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289871 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1NR4A2PARP1 | |
| SCHEMBL2623143 | 0.72 | XDH (0.65) | XDHPOLBBCHETRPC3TRPC4 | |
| SCHEMBL16306349 | 0.70 | PARP1 (0.60) | KDM4EPARP1HTT | |
| SCHEMBL30289853 | 0.69 | MAPT (0.48) | POLBKDM4ELMNAPARP1MEN1 | |
| SCHEMBL30289906 | 0.69 | POLA1 (0.57) | POLBALDH1A1LMNAMEN1HTT | |
| SCHEMBL23114951 | 0.69 | XDH (0.54) | XDHPOLBBCHETRPC3TRPC4 | |
| SCHEMBL249648 | 0.69 | XDH (0.66) | XDHPOLBBCHETRPC3TRPC4 | |
| SCHEMBL30289911 | 0.68 | POLA1 (0.41) | POLBKDM4EALDH1A1LMNAPARP1 | |
| SCHEMBL8535455 | 0.68 | XDH (0.67) | XDHBCHETRPC3TRPC4TRPC5 | |
| SCHEMBL25668394 | 0.67 | KDM4E (0.43) | XDHPOLBBCHETRPC3TRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |