Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289853 | 0.86 | MAPT (0.48) | POLA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL30289911 | 0.83 | POLA1 (0.41) | POLA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL30289910 | 0.81 | POLA1 (0.55) | POLA1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL30289893 | 0.75 | AKT1 (0.40) | RAB9ASMN1; SMN2LCKALDH1A1 | |
| SCHEMBL30289871 | 0.74 | KDM4E (0.49) | LCKALDH1A1 | |
| SCHEMBL30289899 | 0.73 | CXCR2 (0.41) | POLA1LCK | |
| SCHEMBL22245126 | 0.70 | POLA1 (0.50) | POLA1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL22161999 | 0.70 | POLA1 (0.50) | POLA1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL12344710 | 0.69 | POLA1 (0.49) | POLA1MAPTKMT2ACYP3A4RECQL | |
| SCHEMBL30289877 | 0.69 | XDH (0.49) | MEN1KMT2ALMNAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |