Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 7/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289893 | 0.84 | AKT1 (0.40) | CXCR2LCKEGFRKDRNAMPT | |
| SCHEMBL30289911 | 0.76 | POLA1 (0.41) | LCKEGFRSRCZAP70PARP1 | |
| SCHEMBL30289853 | 0.76 | MAPT (0.48) | LCKEGFRSRCZAP70PARP1 | |
| SCHEMBL30289906 | 0.73 | POLA1 (0.57) | LCKPOLA1 | |
| SCHEMBL30289871 | 0.70 | KDM4E (0.49) | CXCR2LCKEGFRSRCZAP70 | |
| SCHEMBL16306345 | 0.66 | PARP1 (0.54) | PARP1TYMS | |
| SCHEMBL16306347 | 0.66 | PARP1 (0.54) | PARP1TYMS | |
| SCHEMBL30289877 | 0.66 | XDH (0.49) | PARP1 | |
| SCHEMBL16306349 | 0.65 | PARP1 (0.60) | PARP1TYMS | |
| SCHEMBL1996015 | 0.64 | GAA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054759-A1 | 2-AMINOQUINAZOLINE DERIVATIVE AND ANTI-VIRAL COMPOSITION COMPRISING SAME | 한국화학연구원 | 2023-04-06 | — | — | WO | disclosed |