Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291262 | 0.86 | HTR2A (0.31) | HTR2A | |
| SCHEMBL23645053 | 0.86 | HTR2A (0.31) | HTR2A | |
| SCHEMBL23645686 | 0.83 | — | — | |
| SCHEMBL23644323 | 0.74 | HDAC4 (0.32) | — | |
| SCHEMBL30291255 | 0.73 | APAF1 (0.31) | — | |
| SCHEMBL23645219 | 0.72 | TRPA1 (0.34) | HTR2A | |
| SCHEMBL23645472 | 0.72 | SIGMAR1 (0.36) | HTR2A | |
| SCHEMBL23645506 | 0.69 | HDAC4 (0.32) | — | |
| SCHEMBL24483057 | 0.65 | SLC18A3 (0.56) | — | |
| SCHEMBL23644320 | 0.64 | OPRM1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087700-B | Spirocyclic tetrahydroquinazolines | 苏州亚盛药业有限公司 | 2023-03-14 | — | — | CN | disclosed |