Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039337 | 0.92 | PDK1 (0.48) | TACR1PDK1SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3039331 | 0.89 | TACR1 (0.45) | TACR1PDK1SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3029477 | 0.89 | TACR1 (0.48) | TACR1PDK1SLC6A4OPRD1SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL3039321 | 0.84 | OPRD1 (0.52) | SLC6A4OPRD1SLC6A2SLC6A3CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL3042529 | 0.83 | OPRD1 (0.41) | TACR1PDK1SLC6A4OPRD1SLC6A2 | |
| SCHEMBL3039335 | 0.82 | TACR1 (0.49) | TACR1PDK1SLC6A4SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3032309 | 0.82 | OPRM1 (0.40) | SLC6A4OPRD1SLC6A2SLC6A3KCNH2 | |
| SCHEMBL3029498 | 0.81 | PDK1 (0.50) | TACR1PDK1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3035854 | 0.80 | SLC6A4 (0.50) | TACR1PDK1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3029377 | 0.79 | PDK1 (0.48) | PDK1SLC6A4OPRD1SLC6A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2010-08-12 | — | — | US | disclosed |
| EP-2183219-A2 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009016214-A2 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | TACR1 116/4885PDK1 1813/4885SLC6A4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.