Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033983 | 0.93 | ALDH1A1 (0.42) | OPRM1MC4RKDM4EALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL3042529 | 0.88 | OPRD1 (0.41) | OPRD1HSD17B10SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3032574 | 0.87 | CACNA1B (0.42) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3033986 | 0.83 | OPRM1 (0.49) | OPRM1OPRD1KDM4EALDH1A1HTR4 | |
| Trifluoroacetic Acid SCHEMBL3029533 | 0.82 | TACR1 (0.46) | OPRD1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3039339 | 0.81 | GHSR (0.47) | KDM4EALDH1A1LMNAHPGDNPSR1 | |
| Trifluoroacetic Acid SCHEMBL3039321 | 0.81 | OPRD1 (0.52) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3041213 | 0.80 | CACNA1B (0.46) | OPRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3035355 | 0.80 | SLC6A4 (0.43) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL924001 | 0.76 | MC4R (0.49) | EPHX2OPRD1MC4RALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | OPRM1 55/4885EPHX2 1411/4885OPRD1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.