Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.33 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 2/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211031 | 0.62 | ADORA3 (0.34) | ADORA3ADORA2AEPHX2ADORA1MEN1 | |
| SCHEMBL17335905 | 0.59 | PRCP (0.53) | MEN1KMT2APRCP | |
| SCHEMBL17335904 | 0.59 | PRCP (0.53) | MEN1KMT2APRCP | |
| SCHEMBL7659939 | 0.59 | CPB1 (0.49) | EPHX2GAAMEN1KMT2A | |
| SCHEMBL2860494 | 0.59 | SMN1; SMN2 (0.58) | GAADDB1CRBNMEN1KMT2A | |
| SCHEMBL27482299 | 0.59 | ALDH1A1 (0.51) | MEN1KMT2A | |
| SCHEMBL27482300 | 0.59 | ALDH1A1 (0.51) | MEN1KMT2A | |
| SCHEMBL7742811 | 0.58 | ALDH1A1 (0.58) | MEN1KMT2A | |
| SCHEMBL17335891 | 0.58 | MEN1 (0.43) | EPHX2GAAMEN1KMT2APRCP | |
| SCHEMBL18875626 | 0.58 | PRCP (0.59) | MEN1KMT2APRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019834-B1 | ECTONUCLEOTIDASE INHIBITORS | UNIV BONN (DE) | 2014-07-09 | — | — | EP | disclosed |
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | NT5E, NT5C2, ENTPD1 | PRKACA 1691/4885ADORA3 28/4885ADORA2A 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.