Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299337 | 0.81 | CPB1 (0.47) | CPB1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL7296884 | 0.79 | F10 (0.48) | CPB1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL7599619 | 0.77 | ALDH1A1 (0.73) | HTTKMT2AALDH1A1USP2HPGD | |
| SCHEMBL850782 | 0.77 | FABP7 (0.51) | KMT2AALDH1A1HPGDGAAMAPK1 | |
| SCHEMBL7303090 | 0.75 | HTT (0.59) | HTTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL21142117 | 0.75 | SMN1; SMN2 (0.51) | CPB1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL305022 | 0.74 | GLA (0.52) | KMT2AALDH1A1GAAMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6653324 | 0.74 | HTR2C (0.55) | CPB1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL24526798 | 0.74 | ALDH1A1 (0.56) | HTTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13323438 | 0.73 | ALDH1A1 (0.61) | HTTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384065-B1 | CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1076056-A1 | NOVEL SPIRO COMPOUNDS OR SALTS THEREOF AND PREVENTIVES/REMEDIES FOR AUTOIMMUNE DISEASES AND AP-1 INHIBITORS CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |