Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26688859 | 0.85 | LMNA (0.51) | MAPK1TSHRLMNAKDM4EPARP1 | |
| SCHEMBL20778195 | 0.84 | MAPK1 (0.63) | MAPK1TSHRLMNAKDM4EPARP1 | |
| SCHEMBL1891525 | 0.81 | TSHR (0.43) | MAPK1TSHRLMNAKDM4EPARP1 | |
| SCHEMBL26688878 | 0.81 | PKM (0.41) | MAPK1TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL9490757 | 0.79 | KDM4E (0.50) | MAPK1TSHRLMNAKDM4EPARP1 | |
| SCHEMBL2227651 | 0.75 | LMNA (0.39) | TSHRLMNAKDM4EPOLBL3MBTL1 | |
| SCHEMBL25778574 | 0.75 | KDM4E (0.55) | LMNAKDM4EPARP1POLBL3MBTL1 | |
| SCHEMBL26688805 | 0.74 | PKM (0.63) | TSHRKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL20778200 | 0.74 | KDM4E (0.52) | TSHRLMNAKDM4EPARP1L3MBTL1 | |
| SCHEMBL9487922 | 0.73 | PARP1 (0.51) | MAPK1KDM4EPARP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |