Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229077 | 0.85 | LMNA (0.45) | LMNAALDH1A1POLBHTTRXFP1 | |
| SCHEMBL28619888 | 0.82 | POLB (0.45) | LMNAALDH1A1POLBHTTRXFP1 | |
| SCHEMBL9843881 | 0.81 | MAPT (0.37) | LMNACYP2C19ALDH1A1POLBHTT | |
| SCHEMBL28628793 | 0.80 | TSHR (0.53) | LMNAKDM4ETSHRTLR7 | |
| SCHEMBL29703417 | 0.80 | TSHR (0.53) | LMNAKDM4ETSHRTLR7 | |
| SCHEMBL9843662 | 0.78 | MAPT (0.37) | LMNACYP2C19ALDH1A1POLBHTT | |
| SCHEMBL8805901 | 0.77 | ALDH1A1 (0.44) | LMNAALDH1A1ATMMAPTL3MBTL1 | |
| SCHEMBL27477358 | 0.76 | MAPT (0.38) | LMNACYP2C19ALDH1A1POLBHTT | |
| SCHEMBL30296207 | 0.75 | MAPK1 (0.43) | LMNAALDH1A1POLBKDM4ETHRB | |
| SCHEMBL9253828 | 0.75 | MAPK1 (0.44) | LMNAALDH1A1KDM4EATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011090323-A2 | NOVEL PREPARATION METHOD OF 2-(2-N-BUTYL-4-HYDROXY-6-METHYL-PYRIMIDIN-5-YL)-N,N-DIMETHYLACETAMIDE | BORYUNG PHARMACEUTICAL CO., LTD (KR) | 2011-07-28 | — | — | WO | claimed |
| CN-102666496-B | Preparation method of 2- (2-N-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl) -N, N-dimethylacetamide | BORYUNG PHARM | 2015-05-20 | — | — | CN | disclosed |
| CN-102666496-B | Preparation method of 2- (2-N-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl) -N, N-dimethylacetamide | BORYUNG PHARM | 2015-05-20 | — | — | CN | disclosed |
| CN-104610164-A | New preparation of 2-(2-n-butyl-4-hydroxy-6-methyl-pyrimidine-5-yl)-n,n-dimethylacetamide | BORYUNG PHARM | 2015-05-13 | — | — | CN | disclosed |
| CN-104610164-A | New preparation of 2-(2-n-butyl-4-hydroxy-6-methyl-pyrimidine-5-yl)-n,n-dimethylacetamide | BORYUNG PHARM | 2015-05-13 | — | — | CN | disclosed |
| CN-102666496-A | New preparation method of 2- (2-N-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl) -N, N-dimethylacetamide | BORYUNG PHARM | 2012-09-12 | — | — | CN | disclosed |
| CN-102666496-A | New preparation method of 2- (2-N-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl) -N, N-dimethylacetamide | BORYUNG PHARM | 2012-09-12 | — | — | CN | disclosed |
| WO-2011090323-A3 | NOVEL PREPARATION METHOD OF 2-(2-N-BUTYL-4-HYDROXY-6-METHYL-PYRIMIDIN-5-YL)-N,N-DIMETHYLACETAMIDE | BORYUNG PHARMACEUTICAL CO., LTD (KR) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011090323-A3 | NOVEL PREPARATION METHOD OF 2-(2-N-BUTYL-4-HYDROXY-6-METHYL-PYRIMIDIN-5-YL)-N,N-DIMETHYLACETAMIDE | BORYUNG PHARMACEUTICAL CO., LTD (KR) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011090323-A2 | NOVEL PREPARATION METHOD OF 2-(2-N-BUTYL-4-HYDROXY-6-METHYL-PYRIMIDIN-5-YL)-N,N-DIMETHYLACETAMIDE | BORYUNG PHARMACEUTICAL CO., LTD (KR) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011090323-A2 | NOVEL PREPARATION METHOD OF 2-(2-N-BUTYL-4-HYDROXY-6-METHYL-PYRIMIDIN-5-YL)-N,N-DIMETHYLACETAMIDE | BORYUNG PHARMACEUTICAL CO., LTD (KR) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011090323-A2 | NOVEL PREPARATION METHOD OF 2-(2-N-BUTYL-4-HYDROXY-6-METHYL-PYRIMIDIN-5-YL)-N,N-DIMETHYLACETAMIDE | BORYUNG PHARMACEUTICAL CO., LTD (KR) | 2011-07-28 | — | — | WO | disclosed |