SCHEMBL30299062

SCHEMBL30299062

COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.44
CA2 P00918 8/20 0.44
MMP2 P08253 3/20 0.43
MMP9 P14780 3/20 0.43
MMP1 P03956 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
RECQL P46063 1/20 0.42
NPY5R Q15761 4/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.41
CA12 O43570 3/20 0.41
CA9 Q16790 3/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25352826 1.00 CA1 (0.44) CA1CA2MMP2MMP9MMP1
SCHEMBL30299067 0.97 CA1 (0.44) CA1CA2MMP2MMP9MMP1
SCHEMBL20556384 0.93 CA1 (0.45) CA1CA2MMP2MMP9MMP1
SCHEMBL20556383 0.93 CA1 (0.45) CA1CA2MMP2MMP9MMP1
SCHEMBL25352953 0.91 MMP2 (0.50) CA1CA2MMP2MMP9MMP1
SCHEMBL25352949 0.91 MMP2 (0.50) CA1CA2MMP2MMP9MMP1
SCHEMBL25354041 0.89 MMP2 (0.46) CA1CA2MMP2MMP9MMP1
SCHEMBL12287583 0.89 MMP2 (0.46) CA1CA2MMP2MMP9MMP1
SCHEMBL25354045 0.89 MMP2 (0.46) CA1CA2MMP2MMP9MMP1
SCHEMBL30517734 0.87 MMP9 (0.41) CA1CA2MMP2MMP9MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109732-A1 LIPID AMINES MODERNATX INC (US) 2026-04-23 US disclosed
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2025-07-24 US disclosed
EP-4475882-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS ModernaTX, Inc. (US) 2024-12-18 EP disclosed
EP-4423107-A1 LIPID AMINES ModernaTX, Inc. (US) 2024-09-04 EP disclosed
CN-118510788-A Liposoamines 摩登纳特斯有限公司 2024-08-16 CN disclosed
WO-2023076598-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MUC1, RNMT, FABP2 CA1 4350/4885CA2 4557/4885MMP2 3646/4885
US-20260109732-A1 LIPID AMINES LDLR, NPC1, PHOSPHO1 CA1 1889/4885CA2 3992/4885MMP2 3897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.