Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299376 | 0.89 | GPR4 (0.38) | LTA4H | |
| SCHEMBL30299272 | 0.87 | LTA4H (0.46) | LTA4HHRH3APPSIGMAR1MAPK1 | |
| SCHEMBL30299400 | 0.86 | LTA4H (0.47) | LTA4HHRH3APPSIGMAR1MAPK1 | |
| SCHEMBL30299380 | 0.85 | PRKCQ (0.31) | — | |
| SCHEMBL4987905 | 0.82 | GPR4 (0.33) | MAPT | |
| SCHEMBL30299362 | 0.82 | GPR4 (0.33) | MAPT | |
| SCHEMBL30299358 | 0.78 | GPR4 (0.43) | LTA4HHRH3 | |
| SCHEMBL30299348 | 0.76 | GPR4 (0.42) | LTA4HHRH3 | |
| SCHEMBL30299395 | 0.76 | TSHR (0.38) | LTA4HSIGMAR1MAPK1 | |
| SCHEMBL30299386 | 0.76 | SIGMAR1 (0.40) | LTA4HHRH3SIGMAR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |