Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299400 | 0.99 | LTA4H (0.47) | LTA4HHRH3APPMAPK1SIGMAR1 | |
| SCHEMBL30299358 | 0.89 | GPR4 (0.43) | LTA4HHRH3ALDH1A1TSHROPRM1 | |
| SCHEMBL30299395 | 0.88 | TSHR (0.38) | LTA4HMAPK1SIGMAR1LMNAALDH1A1 | |
| SCHEMBL30299386 | 0.88 | SIGMAR1 (0.40) | LTA4HHRH3MAPK1SIGMAR1LMNA | |
| SCHEMBL30299348 | 0.88 | GPR4 (0.42) | LTA4HHRH3LMNAALDH1A1TSHR | |
| SCHEMBL30299279 | 0.87 | LTA4H (0.36) | LTA4HHRH3APPMAPK1SIGMAR1 | |
| SCHEMBL30299374 | 0.85 | SMN1; SMN2 (0.35) | LTA4HLMNAKDM4ESMN1; SMN2GAA | |
| SCHEMBL30299394 | 0.85 | GPR4 (0.43) | HRH3MAPK1SIGMAR1LMNAALDH1A1 | |
| SCHEMBL30299399 | 0.81 | GPR4 (0.37) | SIGMAR1LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL30299397 | 0.79 | ALDH1A1 (0.33) | HRH3SIGMAR1ALDH1A1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |