Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929683 | 0.91 | AXL (0.40) | SMN1; SMN2ALDH1A1AXLLMNA | |
| SCHEMBL30090486 | 0.90 | KCNH2 (0.39) | ALDH1A1AXLKCNH2HTR1A | |
| SCHEMBL29928123 | 0.90 | AXL (0.39) | SMN1; SMN2ALDH1A1AXL | |
| SCHEMBL30090654 | 0.88 | PDE3B (0.34) | SMN1; SMN2HPGDALDH1A1AXLNPC1 | |
| SCHEMBL30299345 | 0.88 | AXL (0.38) | SMN1; SMN2ALDH1A1AXLLMNA | |
| SCHEMBL30299260 | 0.87 | VCP (0.36) | AXLKCNH2HTR1A | |
| SCHEMBL30299369 | 0.87 | AXL (0.37) | SMN1; SMN2ALDH1A1KDM4EAXLKMT2A | |
| SCHEMBL30090687 | 0.86 | AXL (0.38) | GAAALDH1A1KDM4EAXLKMT2A | |
| SCHEMBL30299377 | 0.84 | PDE3B (0.34) | GAASMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL30090537 | 0.82 | TNIK (0.36) | GAAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |