Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929683 | 0.87 | AXL (0.40) | ALDH1A1LMNASMN1; SMN2HRH3 | |
| SCHEMBL30090537 | 0.87 | TNIK (0.36) | GAA | |
| SCHEMBL29928123 | 0.86 | AXL (0.39) | ALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL30299371 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL30299369 | 0.84 | AXL (0.37) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL30299398 | 0.84 | OPRM1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30090654 | 0.84 | PDE3B (0.34) | PDE3BPDE3AALDH1A1LMNAMAPK1 | |
| SCHEMBL30299330 | 0.84 | GAA (0.34) | SMN1; SMN2GAAHPGD | |
| SCHEMBL30299303 | 0.84 | CYP17A1 (0.36) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL30299381 | 0.84 | IP6K1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |