Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.55 |
| ▸ | CLK1 | P49759 | 4/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.55 |
| ▸ | CLK2 | P49760 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651697 | 0.85 | DYRK1A (0.54) | DYRK1ACLK4CLK1DYRK1BCLK2 | |
| SCHEMBL24334967 | 0.83 | PTGS2 (0.64) | DYRK1ACLK4CLK1DYRK1BCLK2 | |
| SCHEMBL30299494 | 0.79 | CDK4 (0.54) | VCPABL1EGFRPRKCAPRKCD | |
| SCHEMBL11551000 | 0.79 | CDC7 (0.61) | CLK4CDC7CYP3A4 | |
| SCHEMBL22191614 | 0.78 | DYRK1A (0.54) | DYRK1ACLK4CLK1DYRK1BCLK2 | |
| SCHEMBL10441707 | 0.77 | ATM (0.55) | CDC7LCKCYP3A4 | |
| SCHEMBL12597156 | 0.77 | NPSR1 (0.55) | CDC7LCK | |
| SCHEMBL22191109 | 0.77 | LCK (0.50) | HDAC3HDAC1HDAC2HDAC6CDC7 | |
| SCHEMBL18608757 | 0.77 | CDC7 (0.52) | CLK4CDC7LCK | |
| SCHEMBL29836535 | 0.77 | ATM (0.55) | CDC7LCKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-11-21 | — | — | US | disclosed |
| WO-2023043292-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | 기초과학연구원 | 2023-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | NUDT1, UMPS, DPYD | DYRK1A 1573/4885CLK4 1913/4885CLK1 2336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.