Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299573 | 0.79 | DYRK1A (0.55) | CDK2VCPABL1EGFRPRKCA | |
| SCHEMBL91472 | 0.73 | CDK4 (0.46) | CDK4CDK2ALDH1A1MAPTTP53 | |
| SCHEMBL17700115 | 0.73 | ALDH1A1 (0.54) | CDK4CDK2GPR39ALDH1A1 | |
| SCHEMBL11471935 | 0.73 | AGTR1 (0.63) | VCPABL1EGFRPRKCAPRKCD | |
| SCHEMBL5316895 | 0.73 | TDP1 (0.63) | VCPABL1EGFRPRKCAPRKCD | |
| SCHEMBL5100516 | 0.73 | VCP (0.47) | CDK2VCPABL1EGFRPRKCA | |
| SCHEMBL21376389 | 0.73 | VCP (0.56) | VCPABL1EGFRPRKCAPRKCD | |
| SCHEMBL5089075 | 0.72 | OGA (0.53) | CDK2VCPUSP30AURKAPIK3CG | |
| SCHEMBL1593016 | 0.71 | PRKCD (0.79) | CDK4CDK2ABL1EGFRPRKCA | |
| Gw683003X SCHEMBL4473027 | 0.71 | CDK2 (1.00) | CDK4CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-11-21 | — | — | US | disclosed |
| WO-2023043292-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | 기초과학연구원 | 2023-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383863-A1 | PREPARATION METHOD FOR PYRIMIDINE-2-AMINE | NUDT1, UMPS, DPYD | CDK4 880/4885CDK2 98/4885VCP 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.