Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704320 | 0.85 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL1703768 | 0.85 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL1389175 | 0.81 | PKM (0.74) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2530312 | 0.79 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL835070 | 0.78 | NAMPT (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2533805 | 0.78 | SMN1; SMN2 (0.62) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL30300538 | 0.78 | MAPK1 (0.69) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1703824 | 0.78 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL10055020 | 0.77 | NPC1 (0.94) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL4436642 | 0.77 | KCNK3 (0.77) | RAB9ANPC1SMN1; SMN2RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028117-A1 | METHODS OF TREATING CDGSH IRON SULFUR DOMAIN 2 INSUFFICIENCY-ASSOCIATED DISORDERS | YEH, TENG-KUANG (US) | 2023-03-02 | — | — | WO | disclosed |