Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526242 | 1.00 | MLYCD (0.36) | MLYCDCACNA1GCACNA1BCACNA1CBACE1 | |
| SCHEMBL30014266 | 0.94 | MLYCD (0.38) | MLYCDCACNA1GCACNA1BCACNA1CBACE1 | |
| SCHEMBL25839091 | 0.94 | MLYCD (0.38) | MLYCDCACNA1GCACNA1BCACNA1CBACE1 | |
| SCHEMBL30014032 | 0.84 | THRA (0.33) | MLYCDCACNA1GCACNA1BCACNA1C | |
| SCHEMBL442484 | 0.73 | LMNA (0.40) | EPHX2 | |
| SCHEMBL29945782 | 0.73 | MLYCD (0.43) | MLYCDEPHX2RORC | |
| SCHEMBL23526088 | 0.73 | MLYCD (0.43) | MLYCDEPHX2RORC | |
| SCHEMBL18146720 | 0.70 | — | — | |
| SCHEMBL31643114 | 0.69 | MLYCD (0.40) | MLYCDEPHX2 | |
| SCHEMBL28880360 | 0.69 | MLYCD (0.40) | MLYCDEPHX2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358963-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271679-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |