Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482824 | 0.78 | BACE1 (0.44) | ENPP3ENPP1BACE1CA2CHKA | |
| SCHEMBL31256474 | 0.77 | NOTUM (0.33) | BACE1CA2CHKAKDM4E | |
| SCHEMBL31322072 | 0.70 | CFTR (0.35) | KDM4E | |
| SCHEMBL26059013 | 0.70 | BACE1 (0.31) | BACE1 | |
| SCHEMBL24738092 | 0.69 | CA2 (0.33) | CA2CHKA | |
| SCHEMBL31256275 | 0.69 | LMNA (0.41) | BACE1 | |
| SCHEMBL503229 | 0.69 | BACE1 (0.40) | BACE1KDM4E | |
| SCHEMBL21963087 | 0.68 | ENPP3 (0.35) | ENPP3ENPP1 | |
| SCHEMBL30302014 | 0.67 | KDM4E (0.35) | KDM4E | |
| SCHEMBL2478082 | 0.67 | BACE1 (0.44) | ENPP3ENPP1BACE1CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358963-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271679-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |