Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322072 | 0.89 | CFTR (0.35) | KDM4ECFTRIDO1 | |
| SCHEMBL31322042 | 0.72 | SMN1; SMN2 (0.40) | KDM4ECFTRIDO1 | |
| SCHEMBL2482824 | 0.69 | BACE1 (0.44) | KDM4ECFTR | |
| SCHEMBL30302012 | 0.67 | ENPP3 (0.33) | KDM4E | |
| SCHEMBL14968912 | 0.63 | RCE1 (0.38) | KDM4ECFTRIDO1 | |
| SCHEMBL14966182 | 0.59 | TBK1 (0.40) | KDM4ECFTRIDO1 | |
| SCHEMBL20073770 | 0.59 | GABRP (0.55) | KDM4EIDO1 | |
| SCHEMBL29883463 | 0.59 | GABRP (0.55) | KDM4EIDO1 | |
| SCHEMBL14969004 | 0.59 | IKBKB (0.36) | KDM4EIDO1 | |
| SCHEMBL21963087 | 0.59 | ENPP3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358963-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271679-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |