SCHEMBL30306100

SCHEMBL30306100

COCc1cccc(CBr)c1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
IDO1 P14902 6/20 0.41
AGXT P21549 4/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
MAOB P27338 4/20 0.40
FFAR1 O14842 1/20 0.39
ERN1 O75460 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567905 1.00 TRPA1 (0.42) TRPA1ALDH1A1TSHRIDO1AGXT
SCHEMBL487468 0.89 IDO1 (0.48) IDO1AGXTMAOBFFAR1ERN1
Methoxymethane SCHEMBL28161427 0.86 TSHR (0.50) TRPA1ALDH1A1TSHRIDO1AGXT
SCHEMBL14508909 0.83 TRPA1 (0.39) TRPA1ALDH1A1TSHRIDO1AGXT
SCHEMBL27826128 0.83 TDP1 (0.46) IDO1AGXTMAOBFFAR1ERN1
SCHEMBL3149674 0.81 PTPN1 (0.46) CYP4F2CYP4A11
SCHEMBL348159 0.81 ALDH1A1 (0.61) TRPA1ALDH1A1TSHRIDO1AGXT
SCHEMBL2213709 0.81 ALDH1A1 (0.61) TRPA1ALDH1A1TSHRIDO1AGXT
SCHEMBL12305 0.80 TP53 (0.44) ALDH1A1IDO1AGXTMAOBFFAR1
SCHEMBL21587350 0.79 HTR7 (0.50) ALDH1A1TSHRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869373-B Antibiotic resistance disruptors 伦敦皇家学院 2023-03-07 CN disclosed