Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | CYCS | P99999 | 3/20 | 0.58 |
| ▸ | TERT | O14746 | 4/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL599425 | 1.00 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Tetraphenylporphyrin SCHEMBL29995931 | 0.98 | CYCS (0.61) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL30363117 | 0.98 | TOP1 (0.62) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL29872728 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL29440936 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL5572883 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483551 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483749 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL1465445 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL30909509 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118347997-B | Color developing card for identifying fishy smell degradation degree of burdock drug and preparation and use methods thereof | 江苏省农业科学院 | 2024-10-18 | — | — | CN | claimed |
| CN-118347997-A | Color developing card for identifying fishy smell degradation degree of burdock drug and preparation and use methods thereof | 江苏省农业科学院 | 2024-07-16 | — | — | CN | claimed |
| CN-117924636-A | Preparation method and application of hydrophobic core-shell olfactory sensor | 江苏大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117836298-A | Catalytic glycosylation process for aromatic hydrocarbons | 科勒研究非盈利有限责任公司 | 2024-04-05 | — | — | CN | claimed |
| CN-110987895-B | Method for rapidly detecting growth process of cassava solid state fermentation on line | 江苏大学 | 2023-04-11 | — | — | CN | claimed |
| US-20240366627-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2024-11-07 | — | — | US | disclosed |
| CN-118347997-B | Color developing card for identifying fishy smell degradation degree of burdock drug and preparation and use methods thereof | 江苏省农业科学院 | 2024-10-18 | — | — | CN | disclosed |
| CN-118347997-A | Color developing card for identifying fishy smell degradation degree of burdock drug and preparation and use methods thereof | 江苏省农业科学院 | 2024-07-16 | — | — | CN | disclosed |
| CN-117924636-A | Preparation method and application of hydrophobic core-shell olfactory sensor | 江苏大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117836298-A | Catalytic glycosylation process for aromatic hydrocarbons | 科勒研究非盈利有限责任公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-111788477-B | Graphene non-covalent surface modified chemical varactor-based sensor | 明尼苏达大学董事会 | 2023-06-23 | — | — | CN | disclosed |
| CN-110987895-B | Method for rapidly detecting growth process of cassava solid state fermentation on line | 江苏大学 | 2023-04-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366627-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | MKI67, MYLK2, MYH2 | TOP1 861/4885STAT3 324/4885STAT1 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.