SCHEMBL15923397

SCHEMBL15923397

c1ccc(Oc2ccccc2Nc2ccnc3ccccc23)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.68
HTT P42858 1/20 0.51
RIPK2 O43353 2/20 0.49
GAK O14976 1/20 0.49
COQ8A Q8NI60 1/20 0.49
NLK Q9UBE8 1/20 0.49
CCNC P24863 1/20 0.49
CDK8 P49336 1/20 0.49
POLB P06746 1/20 0.48
THRB P10828 1/20 0.48
HTR1A P08908 2/20 0.47
ADRA1D P25100 2/20 0.47
ADRA1A P35348 2/20 0.47
ADRA1B P35368 2/20 0.47
FADS1 O60427 1/20 0.46
EGFR P00533 1/20 0.46
KDR P35968 1/20 0.45
FERMT2 Q96AC1 1/20 0.43
HDAC3 O15379 1/20 0.43
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31197392 1.00 ERBB2 (0.68) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL30307397 0.82 GAK (0.66) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL19283173 0.82 GAK (0.66) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL1387165 0.81 ERBB2 (1.00) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL6752938 0.80 HTR1A (0.68) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL8933763 0.80 ERBB2 (0.77) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL15923896 0.80 POLB (0.52) ERBB2HTTRIPK2GAKCOQ8A
Hydrochloric Acid SCHEMBL8812168 0.79 ERBB2 (0.97) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL19283194 0.78 C1R (0.53) ERBB2HTTRIPK2GAKCOQ8A
SCHEMBL1897179 0.77 ERBB2 (0.55) ERBB2HTTPOLBEGFRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2025-01-30 US claimed
US-20180298000-A1 AMINOQUINOLINE COMPOUNDS HAVING ANTICANCER ACTIVITY PHARMA CINQ, LLC 2018-10-18 US claimed
CN-108250142-A Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity 维尔斯达医疗公司 2018-07-06 CN claimed
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2015-12-17 US claimed
EP-2950649-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY Wellstat Therapeutics Corporation (US) 2015-12-09 EP claimed
CN-104968200-A Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity WELLSTAT THERAPEUTICS CORP 2015-10-07 CN claimed
WO-2014120995-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY WELLSTAT THERAPEUTICS CORPORATION (US) 2014-08-07 WO claimed
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2025-01-30 US disclosed
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity PHARMA CINQ, LLC (US) 2024-11-12 US disclosed
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2021-06-03 US disclosed
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2021-06-03 US disclosed
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity WELLSTAT THERAPEUTICS CORPORATION (US) 2021-03-02 US disclosed
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity WELLSTAT THERAPEUTICS CORPORATION (US) 2021-03-02 US disclosed
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2015-12-17 US disclosed
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2015-12-17 US disclosed
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2015-12-17 US disclosed
EP-2950649-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY Wellstat Therapeutics Corporation (US) 2015-12-09 EP disclosed
CN-104968200-A Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity WELLSTAT THERAPEUTICS CORP 2015-10-07 CN disclosed
WO-2014120995-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY WELLSTAT THERAPEUTICS CORPORATION (US) 2014-08-07 WO disclosed
WO-2014120995-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY WELLSTAT THERAPEUTICS CORPORATION (US) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY NOD1, NLRP3, AADAC ERBB2 3364/4885HTT 2154/4885RIPK2 2572/4885
US-20180298000-A1 AMINOQUINOLINE COMPOUNDS HAVING ANTICANCER ACTIVITY MYC, AAAS, ASNS ERBB2 2185/4885HTT 2422/4885RIPK2 3260/4885
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY AADAC, CASP1, AAAS ERBB2 2940/4885HTT 1664/4885RIPK2 3671/4885
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY AADAC, CASP1, AAAS ERBB2 2940/4885HTT 1664/4885RIPK2 3671/4885
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity NOD1, NLRP3, AADAC ERBB2 3364/4885HTT 2154/4885RIPK2 2572/4885
US-10934284-B2 Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity AAAS, AADAC, NFKBIA ERBB2 3154/4885HTT 2024/4885RIPK2 3096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.