Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194506 | 0.80 | ALDH1A1 (0.42) | ENPEPALDH1A1MAPTPTGS1 | |
| SCHEMBL31237035 | 0.80 | ALDH1A1 (0.42) | CTSCOPRM1ALDH1A1MAPTPTGS1 | |
| SCHEMBL31413983 | 0.80 | ALDH1A1 (0.42) | CTSCOPRM1ALDH1A1MAPTPTGS1 | |
| SCHEMBL31344450 | 0.80 | ALDH1A1 (0.42) | CTSCOPRM1ALDH1A1MAPTPTGS1 | |
| SCHEMBL30811186 | 0.74 | MMP1 (0.44) | — | |
| SCHEMBL31520397 | 0.73 | DPP4 (0.51) | ENPEP | |
| SCHEMBL26263797 | 0.71 | DPP4 (0.47) | ENPEP | |
| SCHEMBL30684497 | 0.71 | DPP4 (0.47) | ENPEP | |
| SCHEMBL5579158 | 0.70 | MME (0.43) | CTSC | |
| SCHEMBL5579160 | 0.70 | MME (0.43) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11613547-B2 | G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment | UNIVERSITY OF HEALTH SCIENCES & PHARMACY IN ST. LOUIS (US) | 2023-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11613547-B2 | G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment | OPRK1, OPRL1, ARRB1 | CTSC 2343/4885OPRM1 5/4885ENPEP 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.