Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743845 | 1.00 | PKM (0.54) | PKMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2472213 | 0.85 | ALDH1A1 (0.59) | PKMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3245898 | 0.84 | MAPT (0.51) | PKMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL30309628 | 0.83 | PKM (0.54) | PKMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20743638 | 0.83 | PKM (0.54) | PKMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20743797 | 0.83 | PKM (0.54) | PKMKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2472829 | 0.82 | APEX1 (0.54) | KMT2AALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL16509809 | 0.79 | S1PR1 (0.44) | KMT2AMEN1MAPTALDH1A1PDE4A | |
| SCHEMBL19771455 | 0.79 | LMNA (0.54) | PKMALDH1A1GAAMAPK1HTT | |
| SCHEMBL20743599 | 0.78 | ALDH1A1 (0.56) | PKMKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997651-B | Novel tetrazole compounds and their use in the treatment of tuberculosis | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-01-03 | — | — | CN | disclosed |