SCHEMBL30313491

SCHEMBL30313491

CC(C)C[C@H](NC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 1/20 0.43
▸ MMP3 P08254 1/20 0.43
▸ REN P00797 1/20 0.41
▸ TLR2 O60603 1/20 0.41
▸ TLR1 Q15399 1/20 0.41
▸ FAP Q12884 1/20 0.40
▸ MDM2 Q00987 1/20 0.39
▸ APLNR P35414 1/20 0.38
▸ EPHA2 P29317 1/20 0.38
▸ PSMB9 P28065 1/20 0.38
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ NMUR2 Q9GZQ4 1/20 0.38
▸ NMUR1 Q9HB89 1/20 0.38
▸ OPRM1 P35372 2/20 0.38
▸ OPRK1 P41145 2/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NTSR1 P30989 1/20 0.38
▸ CMA1 P23946 1/20 0.38
▸ RAMP3 O60896 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30313548 0.97 MMP1 (0.42) MMP1MMP3RENTLR2TLR1
SCHEMBL30313483 0.95 MMP1 (0.44) MMP1MMP3RENTLR2TLR1
SCHEMBL30313493 0.93 REN (0.40) MMP1MMP3RENAPLNRNMUR2
SCHEMBL30313541 0.92 MDM2 (0.44) TLR2TLR1MDM2ITGB3ITGA2B
SCHEMBL31297108 0.91 REN (0.46) RENFAPAPLNROPRM1OPRK1
SCHEMBL30313501 0.91 REN (0.40) MMP1MMP3RENAPLNRNMUR2
SCHEMBL30313466 0.90 TLR2 (0.48) TLR2TLR1FAPMDM2ITGB3
SCHEMBL31297104 0.88 REN (0.46) RENTLR2FAPAPLNROPRM1
SCHEMBL31297115 0.86 APLNR (0.45) MMP1MMP3RENTLR2APLNR
SCHEMBL30313512 0.85 RAMP3 (0.38) MMP1MMP3RENAPLNRNMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-11613558-B2 Peptides and pharmaceutical compositions for treating eye diseases YUYU PHARMA, INC. (KR) 2023-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR MMP1 728/4885MMP3 480/4885REN 907/4885
US-11613558-B2 Peptides and pharmaceutical compositions for treating eye diseases VIP, IAPP, SCTR MMP1 728/4885MMP3 480/4885REN 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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