SCHEMBL30313501

SCHEMBL30313501

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 1/20 0.40
▸ RAMP3 O60896 8/20 0.40
▸ CALCR P30988 8/20 0.40
▸ MMP1 P03956 1/20 0.39
▸ MMP3 P08254 1/20 0.39
▸ APLNR P35414 2/20 0.39
▸ PTPN1 P18031 2/20 0.38
▸ NMUR2 Q9GZQ4 1/20 0.38
▸ NMUR1 Q9HB89 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30313493 0.98 REN (0.40) RENRAMP3CALCRMMP1MMP3
SCHEMBL30313548 0.94 MMP1 (0.42) RENRAMP3CALCRMMP1MMP3
SCHEMBL30313512 0.92 RAMP3 (0.38) RENRAMP3CALCRMMP1MMP3
SCHEMBL30313491 0.91 MMP1 (0.43) RENRAMP3CALCRMMP1MMP3
SCHEMBL30313483 0.91 MMP1 (0.44) RENMMP1MMP3APLNR
SCHEMBL30313541 0.86 MDM2 (0.44) —
SCHEMBL31297104 0.85 REN (0.46) RENAPLNR
SCHEMBL30313550 0.85 RAMP3 (0.40) RENRAMP3CALCRMMP1MMP3
SCHEMBL31297108 0.83 REN (0.46) RENAPLNR
SCHEMBL31655749 0.83 F2 (0.40) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-11613558-B2 Peptides and pharmaceutical compositions for treating eye diseases YUYU PHARMA, INC. (KR) 2023-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR REN 907/4885RAMP3 1391/4885CALCR 145/4885
US-11613558-B2 Peptides and pharmaceutical compositions for treating eye diseases VIP, IAPP, SCTR REN 907/4885RAMP3 1391/4885CALCR 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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