SCHEMBL30313550

SCHEMBL30313550

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)CNC(=O)[C@@H]1C[C@@H](OC(C)(C)C)CN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 12/20 0.40
▸ CALCR P30988 12/20 0.40
▸ REN P00797 1/20 0.39
▸ APLNR P35414 2/20 0.39
▸ MMP1 P03956 1/20 0.39
▸ MMP3 P08254 1/20 0.39
▸ MAPK8 P45983 1/20 0.38
▸ MAPK9 P45984 1/20 0.38
▸ MAPK10 P53779 1/20 0.38
▸ NTSR1 P30989 1/20 0.38
▸ OPRM1 P35372 1/20 0.37
▸ OPRD1 P41143 1/20 0.37
▸ NMUR2 Q9GZQ4 1/20 0.37
▸ NMUR1 Q9HB89 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30313512 0.86 RAMP3 (0.38) RAMP3CALCRRENAPLNRMMP1
SCHEMBL30313493 0.85 REN (0.40) RAMP3CALCRRENAPLNRMMP1
SCHEMBL30313501 0.85 REN (0.40) RAMP3CALCRRENAPLNRMMP1
SCHEMBL30313548 0.78 MMP1 (0.42) RAMP3CALCRRENAPLNRMMP1
SCHEMBL30313491 0.77 MMP1 (0.43) RAMP3CALCRRENAPLNRMMP1
SCHEMBL22018515 0.77 APLNR (0.48) RAMP3CALCRAPLNRMAPK8MAPK9
SCHEMBL22380818 0.77 APLNR (0.48) RAMP3CALCRAPLNRMMP1MMP3
SCHEMBL22019188 0.76 APLNR (0.46) RAMP3CALCRRENAPLNRNTSR1
SCHEMBL22019471 0.76 APLNR (0.44) RAMP3CALCRAPLNRMAPK8MAPK9
SCHEMBL22018530 0.75 APLNR (0.43) RAMP3CALCRAPLNRNMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-11613558-B2 Peptides and pharmaceutical compositions for treating eye diseases YUYU PHARMA, INC. (KR) 2023-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR RAMP3 1391/4885CALCR 145/4885REN 907/4885
US-11613558-B2 Peptides and pharmaceutical compositions for treating eye diseases VIP, IAPP, SCTR RAMP3 1391/4885CALCR 145/4885REN 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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