Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607654 | 1.00 | MALT1 (0.43) | MALT1KCNA5DRD2BRD4MEN1 | |
| SCHEMBL24618544 | 0.94 | BRD4 (0.42) | MALT1KCNA5DRD2BRD4TPSAB1 | |
| SCHEMBL29792012 | 0.94 | BRD4 (0.42) | MALT1KCNA5DRD2BRD4TPSAB1 | |
| SCHEMBL24618345 | 0.84 | NQO2 (0.42) | MALT1KCNA5DRD2MEN1KMT2A | |
| SCHEMBL7006722 | 0.83 | MALT1 (0.54) | MALT1DRD2BRD4TPSAB1TPSD1 | |
| SCHEMBL24618673 | 0.80 | MAOB (0.41) | — | |
| SCHEMBL21997347 | 0.79 | ALDH1A1 (0.55) | MALT1PDCD1CD274AKT1SIGMAR1 | |
| SCHEMBL24618412 | 0.78 | DRD2 (0.48) | DRD2MEN1KMT2ANQO2SIGMAR1 | |
| SCHEMBL24618541 | 0.78 | MTNR1A (0.41) | MEN1KMT2APDCD1CD274 | |
| SCHEMBL29792062 | 0.78 | MTNR1A (0.41) | MEN1KMT2APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |