Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 5/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 14/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25292824 | 1.00 | CYP1A2 (0.38) | CYP1A2USP1WDR48RORC | |
| SCHEMBL25792700 | 0.77 | CYP11B2 (0.44) | USP1WDR48RORC | |
| SCHEMBL25792238 | 0.77 | USP1 (0.33) | USP1WDR48RORC | |
| SCHEMBL25792734 | 0.77 | RORC (0.33) | USP1WDR48RORC | |
| SCHEMBL30320412 | 0.74 | GPR119 (0.36) | RORC | |
| SCHEMBL25247862 | 0.74 | GPR119 (0.36) | RORC | |
| SCHEMBL25792288 | 0.72 | USP1 (0.34) | USP1WDR48RORC | |
| SCHEMBL25792645 | 0.72 | RORC (0.38) | USP1WDR48RORC | |
| SCHEMBL25792640 | 0.71 | RORC (0.35) | USP1WDR48RORC | |
| SCHEMBL25792656 | 0.70 | USP1 (0.36) | USP1WDR48RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161494-A1 | NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |