Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28162777 | 0.93 | HTR6 (0.39) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL28026351 | 0.80 | HTR1A (0.39) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL14998625 | 0.80 | HTR1A (0.39) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL25791837 | 0.79 | HTR1A (0.38) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL25791511 | 0.76 | HTR1A (0.37) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL25793903 | 0.76 | HTR1A (0.37) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL28325131 | 0.76 | IDO1 (0.42) | IDO1HTR6P2RX7CYP17A1 | |
| SCHEMBL29864687 | 0.75 | IDO1 (0.38) | IDO1MGLLHTR6HTR1ASLC6A2 | |
| SCHEMBL12093542 | 0.74 | HTR1A (0.57) | IDO1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10036999 | 0.74 | ADRA1A (0.35) | IDO1MGLLHTR6HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161494-A1 | NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |