SCHEMBL30325596

SCHEMBL30325596

COc1cnccc1C1=C[C@H]2CC[C@@H](C1)N2C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CDK9 P50750 14/20 0.45
CCNT1 O60563 12/20 0.45
FABP4 P15090 1/20 0.37
OPRK1 P41145 1/20 0.37
DAGLB Q8NCG7 1/20 0.37
DAGLA Q9Y4D2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31030985 0.87 CDK9 (0.42) CDK9CCNT1
SCHEMBL24212061 0.87 CDK9 (0.42) CDK9CCNT1
SCHEMBL25259922 0.73 ALDH1A1 (0.45)
SCHEMBL25295383 0.73 ALDH1A1 (0.45)
SCHEMBL18043573 0.72 SLC6A2 (0.49)
SCHEMBL21061144 0.71 CAMKK1 (0.41) CDK9CCNT1
SCHEMBL30325528 0.70 CCR2 (0.40) FABP4
SCHEMBL23124168 0.69 SLC6A4 (0.50)
SCHEMBL25279414 0.69 SLC6A2 (0.34) CDK9CCNT1
SCHEMBL25436389 0.68 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115884971-A Substituted piperidine compounds and uses thereof 卫材R&D管理有限公司 2023-03-31 CN disclosed