Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 7/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383987 | 1.00 | HCRTR2 (0.46) | HCRTR2ESR1RORCNR1I2RORA | |
| SCHEMBL28381946 | 0.77 | HCRTR2 (0.46) | HCRTR2ESR1RORCNR1I2RORA | |
| SCHEMBL30326426 | 0.77 | HCRTR2 (0.46) | HCRTR2ESR1RORCNR1I2RORA | |
| SCHEMBL6828511 | 0.75 | HCRTR2 (0.73) | HCRTR2ESR1RORCKDM1A | |
| SCHEMBL28379669 | 0.75 | HDAC8 (0.59) | RORCNR1I2RORANR1H2RORB | |
| SCHEMBL30326249 | 0.75 | HDAC8 (0.59) | RORCNR1I2RORANR1H2RORB | |
| SCHEMBL8657231 | 0.72 | RORC (0.53) | HCRTR2ESR1RORCNR1I2RORA | |
| SCHEMBL30989980 | 0.71 | PBRM1 (0.53) | KDM1AMAOAMAOBPGR | |
| SCHEMBL435225 | 0.71 | PBRM1 (0.53) | KDM1AMAOAMAOBPGR | |
| SCHEMBL28383011 | 0.70 | DRD2 (0.58) | KDM1ALMNABRPF1BRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872243-B | Sulfonamide compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-03-31 | — | — | CN | disclosed |