Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.73 |
| ▸ | RORC | P51449 | 5/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 11/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657231 | 0.82 | RORC (0.53) | HCRTR2RORCESR1KDM1A | |
| SCHEMBL6297504 | 0.80 | ESR1 (0.87) | HCRTR2ESR1CNR1CNR2KEAP1 | |
| SCHEMBL6553128 | 0.80 | HCRTR2 (0.53) | HCRTR2RORCKDM1ACNR1CNR2 | |
| SCHEMBL5604160 | 0.80 | ESR1 (0.73) | ESR1CNR1CNR2KEAP1NFE2L2 | |
| SCHEMBL28133849 | 0.80 | CNR1 (0.69) | HCRTR2RORCESR1CNR1CNR2 | |
| SCHEMBL28897960 | 0.79 | KDM4E (0.55) | HCRTR2RORCKDM1A | |
| SCHEMBL6828361 | 0.79 | PSEN1 (0.52) | HCRTR2RORCKDM1ACNR1CNR2 | |
| SCHEMBL6157398 | 0.77 | ALDH1A1 (0.58) | HCRTR2RORCESR1KDM1A | |
| SCHEMBL3636387 | 0.76 | LMNA (0.63) | HCRTR2KDM1A | |
| SCHEMBL28383987 | 0.75 | HCRTR2 (0.46) | HCRTR2RORCESR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | HCRTR2 411/4885RORC 1611/4885ESR1 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.