SCHEMBL30327364

SCHEMBL30327364

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nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.54
▸ OPRD1 P41143 2/20 0.54
▸ OPRK1 P41145 2/20 0.54
▸ CALCR P30988 4/20 0.54
▸ HCRTR1 O43613 1/20 0.53
▸ HCRTR2 O43614 1/20 0.53
▸ NPY2R P49146 6/20 0.53
▸ NPY4R P50391 6/20 0.53
▸ NPY5R Q15761 6/20 0.53
▸ NPY1R P25929 4/20 0.53
▸ NTSR2 O95665 2/20 0.53
▸ NTSR1 P30989 2/20 0.53
▸ SORT1 Q99523 2/20 0.53
▸ SLC6A2 P23975 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30335654 0.95 NTSR1 (0.55) OPRM1OPRD1OPRK1CALCRNTSR2
SCHEMBL29463750 0.94 CALCR (0.57) OPRM1OPRD1OPRK1CALCRHCRTR1
SCHEMBL30327395 0.92 SLC6A2 (0.55) OPRM1OPRD1OPRK1CALCRNTSR2
SCHEMBL30327462 0.91 SLC6A2 (0.59) OPRM1OPRD1OPRK1NTSR2NTSR1
SCHEMBL30335912 0.90 NPY2R (0.60) NPY2RNPY4RNPY5RNPY1R
SCHEMBL31182475 0.90 CALCR (0.67) CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL32670304 0.89 SLC6A2 (0.54) OPRM1CALCRNPY2RNPY4RNPY5R
SCHEMBL30751612 0.88 CALCR (0.54) OPRM1OPRD1OPRK1CALCRHCRTR1
SCHEMBL32682814 0.88 OPRM1 (0.55) OPRM1OPRD1OPRK1CALCRNPY2R
SCHEMBL30974385 0.88 CALCRL (0.59) OPRM1OPRD1OPRK1NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034197-A1 Peptides and Fragments for Treating Diabetes and Associated Metabolic Diseases BETAVIVE LTD. (IL) 2026-02-05 — — US disclosed
US-12447198-B2 Peptides and fragments for treating diabetes and associated metabolic diseases BETAVIVE LTD. (IL) 2025-10-21 — — US disclosed
US-20230120635-A1 Peptides and Fragments for Treating Diabetes and Associated Metabolic Diseases BETAVIVE LTD. (IL) 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230120635-A1 Peptides and Fragments for Treating Diabetes and Associated Metabolic Diseases IAPP, IGFBP2, IGFBP1 OPRM1 4546/4885OPRD1 4651/4885OPRK1 4387/4885
US-12447198-B2 Peptides and fragments for treating diabetes and associated metabolic diseases IAPP, IGFBP2, IGFBP1 OPRM1 4546/4885OPRD1 4651/4885OPRK1 4387/4885
US-20260034197-A1 Peptides and Fragments for Treating Diabetes and Associated Metabolic Diseases IAPP, GLP1R, IGF1R OPRM1 1900/4885OPRD1 2441/4885OPRK1 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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