Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327637 | 0.84 | CYP11B2 (0.48) | ACACBOPRL1OPRM1HDAC1HDAC2 | |
| SCHEMBL30327956 | 0.83 | HDAC1 (0.39) | ACACBACACAHDAC1HDAC2CYP11B2 | |
| SCHEMBL30327674 | 0.83 | ITGB3 (0.46) | ACACBACACAOPRL1HDAC1HDAC2 | |
| SCHEMBL30327852 | 0.82 | ACACA (0.45) | ACACBACACAHDAC1HDAC2 | |
| SCHEMBL30327914 | 0.79 | ITGB3 (0.44) | ACACBACACAHDAC1HDAC2CYP11B2 | |
| SCHEMBL30327913 | 0.79 | ACACB (0.42) | ACACBACACAHDAC1HDAC2CYP11B2 | |
| SCHEMBL30328213 | 0.79 | CYP11B2 (0.40) | ACACBACACAHDAC1HDAC2CYP11B2 | |
| SCHEMBL30328149 | 0.78 | CYP11B2 (0.43) | ACACBACACAOPRL1HDAC1HDAC2 | |
| SCHEMBL30327636 | 0.78 | CYP11B2 (0.46) | ACACBACACAHDAC1HDAC2CYP11B2 | |
| Hydrochloric Acid SCHEMBL30328124 | 0.78 | OPRL1 (0.47) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |