Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518103 | 0.89 | ALDH1A1 (0.49) | HRH3MTNR1AMTNR1BMAPTKMT2A | |
| SCHEMBL11519087 | 0.87 | HRH3 (0.42) | HRH3MTNR1AMTNR1BMAPTKMT2A | |
| SCHEMBL20961718 | 0.85 | HRH3 (0.40) | HRH3MTNR1AMTNR1BMAPTKMT2A | |
| SCHEMBL10605812 | 0.85 | KMT2A (0.47) | HRH3MTNR1AMTNR1BMAPTKMT2A | |
| SCHEMBL17863879 | 0.80 | TAAR1 (0.43) | HRH3MTNR1AMTNR1BMAPTEGFR | |
| SCHEMBL38650580 | 0.78 | MAPT (0.46) | MAPTKMT2AMEN1TAAR1GAA | |
| SCHEMBL1600066 | 0.78 | ALDH1A1 (0.62) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL9015909 | 0.78 | MAPT (0.46) | MAPTKMT2AMEN1TAAR1GAA | |
| SCHEMBL17863878 | 0.77 | CYP1A2 (0.41) | MTNR1AMTNR1BMAPTTAAR1GAA | |
| SCHEMBL6573422 | 0.77 | HRH3 (0.42) | HRH3MTNR1AMTNR1BMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067900-B2 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) | 2015-06-30 | — | — | US | disclosed |
| CN-101796041-B | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEV P H D | 2013-05-22 | — | — | CN | disclosed |
| EP-2185531-B1 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEV P H D (FR) | 2012-07-25 | — | — | EP | disclosed |
| US-20100204215-A1 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2010-08-12 | — | — | US | disclosed |
| CN-101796041-A | Novel diamino phenothiazine compounds, Its Preparation Method And Use | MA HYDRO DEV P H D | 2010-08-04 | — | — | CN | disclosed |
| EP-2185531-A2 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | Pharma Hydro Development - P.H.D. (FR) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009044054-A2 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2009-04-09 | — | — | WO | disclosed |
| EP-0600045-B1 | HAIR DYE | WELLA AG (DE) | 1996-01-24 | — | — | EP | disclosed |
| US-5409502-A | Acid resistance | WELLA AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| US-4147716-A | Preparation of N-substituted carbamates | BASF WYANDOTTE CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-3997519-A | Method of producing quaternary pyridinium compounds | GAF CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204215-A1 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | AOC1, DDT, DDC | HRH3 2957/4885MTNR1A 3256/4885MTNR1B 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.