Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 8/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30328476 | 0.92 | GPR119 (0.49) | CYP11B2GPR119RETCKS1BSKP1 | |
| SCHEMBL30329263 | 0.90 | CYP11B2 (0.48) | CYP11B2GPR119RETACACBEIF2AK4 | |
| SCHEMBL30409946 | 0.90 | RET (0.43) | CYP11B2GPR119RETEIF2AK4CKS1B | |
| SCHEMBL30898352 | 0.90 | RET (0.43) | CYP11B2GPR119RETEIF2AK4CKS1B | |
| SCHEMBL21521592 | 0.86 | CKS1B (0.55) | GPR119CKS1BSKP1SKP2SLC6A9 | |
| SCHEMBL31296441 | 0.86 | CKS1B (0.55) | GPR119CKS1BSKP1SKP2SLC6A9 | |
| SCHEMBL30328628 | 0.84 | CYP11B2 (0.53) | CYP11B2GPR119RETACACBEIF2AK4 | |
| SCHEMBL30327956 | 0.80 | HDAC1 (0.39) | CYP11B2GPR119ACACBCKS1BSKP1 | |
| SCHEMBL31410466 | 0.79 | GPR119 (0.47) | GPR119CKS1BSKP1SKP2SLC6A9 | |
| SCHEMBL31410460 | 0.79 | GPR119 (0.47) | GPR119CKS1BSKP1SKP2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |