Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 5/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | EIF2AK4 | Q9P2K8 | 3/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 2/20 | 0.39 |
| ▸ | SKP1 | P63208 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409946 | 1.00 | RET (0.43) | RETGPR119EIF2AK4EGLN2CKS1B | |
| SCHEMBL30328958 | 0.90 | CYP11B2 (0.46) | RETGPR119EIF2AK4CKS1BSKP1 | |
| SCHEMBL30329263 | 0.86 | CYP11B2 (0.48) | RETGPR119EIF2AK4CKS1BSKP1 | |
| SCHEMBL21521592 | 0.84 | CKS1B (0.55) | GPR119CKS1BSKP1SKP2SLC6A9 | |
| SCHEMBL31296441 | 0.84 | CKS1B (0.55) | GPR119CKS1BSKP1SKP2SLC6A9 | |
| SCHEMBL30328476 | 0.84 | GPR119 (0.49) | RETGPR119CKS1BSKP1SKP2 | |
| SCHEMBL30408906 | 0.83 | SMN1; SMN2 (0.55) | RETEIF2AK4 | |
| SCHEMBL30898339 | 0.83 | SMN1; SMN2 (0.55) | RETEIF2AK4 | |
| SCHEMBL22092941 | 0.81 | RET (0.49) | RETGPR119EIF2AK4EGLN2CYP11B2 | |
| SCHEMBL23744196 | 0.79 | CHRM2 (0.44) | GPR119EIF2AK4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |