Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | NRP1 | O14786 | 3/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.39 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.38 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.38 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385468 | 0.94 | NRP1 (0.43) | OPRM1NRP1PLK1NMUR2NMUR1 | |
| SCHEMBL31410831 | 0.93 | KEAP1 (0.42) | NRP1CALCRLRAMP1EPHA2CXCR4 | |
| SCHEMBL29823805 | 0.90 | RAMP3 (0.39) | NRP1CXCR4PLK1 | |
| SCHEMBL31415944 | 0.90 | NTSR2 (0.46) | PLK1NMUR2NMUR1NTSR2NTSR1 | |
| SCHEMBL30658569 | 0.89 | NMUR2 (0.40) | OPRM1NRP1CXCR4PLK1NMUR2 | |
| SCHEMBL30658573 | 0.88 | NMUR2 (0.43) | OPRM1NRP1PLK1NMUR2NMUR1 | |
| SCHEMBL30141666 | 0.88 | NAA50 (0.42) | NRP1PLK1 | |
| SCHEMBL31165891 | 0.87 | NRP1 (0.41) | OPRM1NRP1EPHA2CXCR4PLK1 | |
| SCHEMBL29781133 | 0.86 | NAA50 (0.41) | NRP1PLK1NMUR2NMUR1 | |
| SCHEMBL31573975 | 0.86 | OPRM1 (0.48) | OPRM1EPHA2CXCR4NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116251195-A | Paclitaxel targeting peptide conjugate and application thereof | 哈尔滨吉象隆生物技术有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-115869312-A | PDC (polycrystalline diamond compact) antitumor drug as well as preparation method and application thereof | 哈尔滨吉象隆生物技术有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115869312-B | PDC anti-tumor medicine and preparation method and application thereof | 哈尔滨吉象隆生物技术有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-116251195-B | Paclitaxel targeting peptide conjugate and application thereof | 哈尔滨吉象隆生物技术有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116251195-A | Paclitaxel targeting peptide conjugate and application thereof | 哈尔滨吉象隆生物技术有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-115869312-A | PDC (polycrystalline diamond compact) antitumor drug as well as preparation method and application thereof | 哈尔滨吉象隆生物技术有限公司 | 2023-03-31 | — | — | CN | disclosed |