Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 12/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022660 | 0.80 | DPP4 (0.52) | PDK2DPP4BRD4 | |
| SCHEMBL30332252 | 0.78 | DPP4 (0.41) | PDK2DPP4BRD4CREBBPEP300 | |
| SCHEMBL18086771 | 0.73 | PDK2 (0.47) | PDK2BRD4CREBBPEP300KMT2A | |
| SCHEMBL30332210 | 0.73 | PDK2 (0.48) | PDK2BRD4CREBBPEP300 | |
| SCHEMBL30332368 | 0.73 | DPP4 (0.51) | PDK2DPP4 | |
| SCHEMBL8279412 | 0.68 | DPP4 (0.53) | PDK2DPP4NOS3NOS1NOS2 | |
| SCHEMBL20777560 | 0.68 | SMARCA2 (0.47) | PDK2BRD4 | |
| SCHEMBL18045672 | 0.68 | GRM4 (0.60) | PDK2JAK2 | |
| SCHEMBL21672546 | 0.68 | GABRA1 (0.50) | PDK2KMT2AJAK2JAK1TYK2 | |
| SCHEMBL28361331 | 0.67 | TRPA1 (0.42) | DPP4BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046128-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-30 | — | — | WO | disclosed |